Peripheral Blood Findings
The peripheral blood is notable for a marked thrombocytosis.
Trephine Core
The marrow is hypercellular for age with increased megakaryocytes. The megakaryocytes are dispersed throughout the marrow and include frequent large forms with abundant cytoplasm and deeply lobated nuclei.
Significant maturation abnormalities are lacking.
Aspirate
The atypical megakaryocytes are evident on the aspirate smear, including quite large forms with abundant cytoplasm, and deeply lobulated nuclei.
