Bone marrow biopsy showing histiocytes containing intracellular yeasts

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Bone marrow biopsy showing histiocytes containing intracellular yeasts

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Author: Janamejey Gaur, MBBS; Daniel Cameron Daugherty; Amani Al Housseiny; Sakshi Singal; Patrick Costello; Thomas Barklow
Category: Infectious Disease > Fungi > Histoplasmosis
Published Date: 04/16/2026

Bone marrow core biopsy (H&E stain) demonstrating histiocytes containing small oval to ovoid intracellular yeasts measuring approximately 2–4 µm (arrows), consistent with histoplasmosis.

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Bone marrow biopsy showing histiocytes containing intracellular yeasts

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