Immunomodulatory drug-associated hyperpigmentation, palms

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Immunomodulatory drug-associated hyperpigmentation, palms

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Author: Adam Berry DO; Anastazia Hartman MBA, MS; Jensyn Cone Sullivan MD, CABP
Category: Lymphoma: Post-transplant Lymphoproliferative Disorder > Monomorphic Post-transplant Lymphoproliferative Disorder > B-cell Neoplasms > Plasma Cell Myeloma
Published Date: 01/22/2026

Physical exam revealed asymmetric, poorly demarcated, dark-brown macules-to-patches broadly distributed over bilateral palms (Figure). The hyperpigmented areas were not erythematous, painful, or solely intertriginous.

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Immunomodulatory Drug-Associated Skin Hyperpigmentation

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Immunomodulatory drug-associated hyperpigmentation, palms

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