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Extramedullary relapse of acute promyelocytic leukemia in cerebrospinal fluid 2

Extramedullary relapse of acute promyelocytic leukemia in cerebrospinal fluid 2
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Author:  Y. Helen Zhang; Xin Han
Category:  Myeloid Neoplasms and acute leukemia (WHO 2016) > Acute Myeloid Leukemia > Acute Myeloid Leukemia with recurrent genetic abnormalities > AML with t(15;17)(q22;q12); PML-RARA (and variants)
Published Date:  09/10/2025

CSF cytology showed numerous abnormal promyelocytes with prominent cytoplasmic primary granules, some of these cells exhibit butterfly-shaped or bilobed nuclei (Wright-Giemsa stain, panel A; original magnification ×200, panel B; original magnification ×1000).


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