Extranodal Nasal type NK-T cell Lymphoma

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Extranodal Nasal type NK-T cell Lymphoma

#00063539

Author: Hemendra Mhadgut; Bahaaeldin Youssef; Devapiran Jaishankar
Category: Lymphoma: Mature T and NK cell lymphoproliferations
Published Date: 05/10/2021

H and E sections of the nasal turbinate reveals ulcerated mucosa with adjacent inflammation and underlying necrosis (asterisk). There is a diffuse submucosal involvement by a cytological atypical mononuclear cell infiltrate, with small to intermediate size pleomorphic nuclei with condensed chromatin and pale cytoplasm (arrow). Immunohistochemically, the mononuclear cells were positive for CD2, CD3, CD7, CD8, CD56, granzyme B and TIA 1, and were negative for CD20. EBV in situ hybridization reveals diffuse positivity of mononuclear cell to EBER.

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