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Myeloid leukemia of Down syndrome CD61 immunostain
Author:
Kristian T. Schafernak
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Acute Myeloid Leukemia > Myeloid proliferations related to Down syndrome > Myeloid Leukemia associated with Down Syndrome
Published Date: 10/28/2016
Category: Myeloid Neoplasms and acute leukemia (WHO 2016) > Acute Myeloid Leukemia > Myeloid proliferations related to Down syndrome > Myeloid Leukemia associated with Down Syndrome
Published Date: 10/28/2016
CD61 (platelet glycoprotein IIIa) immunostain of the bone marrow from a child with Down syndrome who during infancy had transient abnormal myelopoiesis and later developed myeloid (megakaryoblastic) leukemia. Follow-up is important in such cases because even though the transient abnormal myelopoiesis will usually resolve on its own, myeloid leukemia occurs in 20 to 30% of cases.
