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Pelger-Huet anomaly

Pelger-Huet anomaly
#00060045
 
Author:  Teresa Kraus
Category:  Morphologic variants of normal cells > Morphologic variants of white blood cells > Neutrophil > Abnormal neutrophils > True Pelger Huet
Published Date:  09/17/2015

Pelger-Huet anomaly is a congenital autosomal dominant anomaly in which neutrophil nuclei fail to segment normally. In homozygotes , the nucleus is round. In heterozygotes, most granulocytes have bilobed nuclei ("pince-nez" cells) resembling bands. 

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