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Mycosis fungoides (stage IB) on the limbs and self-healing papules and nodules of lymphomatoid papulosis on the trunk

Mycosis fungoides  (stage IB) on the limbs and self-healing papules and nodules of lymphomatoid papulosis on the trunk
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Author: H. Miles Prince, Sean Whittaker, and Richard T. Hoppe
Category: Lymphoma: Mature T and NK cell lymphoproliferations > Cutaneous T-cell Lymphoma > Mycosis Fungoides
Published Date: 12/09/2012

Patient with patches and plaques of MF (stage IB) on the limbs and self-healing papules and nodules of lymphomatoid papulosis on the trunk. This 40-year-old woman presented with a 2-year history of erythematous patches and plaques over the pelvic girdle area and limbs, which was initially considered to be eczema by her local medical officer. She then presented with a 2-month history of small tumors on the trunk. A diagnostic biopsy showed an infiltrate of large CD30+ anaplastic cells and staging investigations were normal, suggesting a diagnosis of primary cutaneous CD30+ anaplastic lymphoma. However, a biopsy of the “eczematous” rash showed an epidermotropic infiltrate of CD4+ T cells consistent with MF